What is a defining feature of Rett Syndrome?

A defining feature of Rett Syndrome is the progressive loss of manual dexterity and social engagement. This neurological disorder primarily affects females and is characterized by normal early growth and development followed by a noticeable decline in previously acquired skills.

Individuals with Rett Syndrome typically experience a loss of purposeful hand skills, leading to difficulties with daily tasks and communication. Alongside the decline in manual dexterity, there is also often a withdrawal from social interactions, which can manifest as reduced eye contact and decreased interest in engaging with others. This distinct pattern of developmental regression is a hallmark of Rett Syndrome, differentiating it from other developmental disorders that may not exhibit such a sharp decline after initial normal development.

In contrast, the other options do not encapsulate this core feature of Rett Syndrome.